1.河南中医药大学呼吸疾病中医药防治省部共建协同创新中心/河南省中医药防治呼吸病重点实验室,河南省郑州市郑东新区金水东路156号,450046
2.河南中医药大学第一附属医院
3.河南中医药大学第一临床医学院
li_js8@163.com
收稿:2024-09-15,
修回:2024-10-30,
纸质出版:2025-04-02
移动端阅览
袁月,雷斯媛,王佳佳等.以窠囊理论探析气管切开术后并发肉芽组织增生的治疗[J].中医杂志,2025,66(07):746-749.
YUAN Yue,LEI Siyuan,WANG Jiajia,et al.Treatment of Granulation Tissue Hyperplasia after Tracheostomy Based on the Kenang (窠囊) Theory[J].Journal of Traditional Chinese Medicine,2025,66(07):746-749.
袁月,雷斯媛,王佳佳等.以窠囊理论探析气管切开术后并发肉芽组织增生的治疗[J].中医杂志,2025,66(07):746-749. DOI: 10.13288/j.11-2166/r.2025.07.015.
YUAN Yue,LEI Siyuan,WANG Jiajia,et al.Treatment of Granulation Tissue Hyperplasia after Tracheostomy Based on the Kenang (窠囊) Theory[J].Journal of Traditional Chinese Medicine,2025,66(07):746-749. DOI: 10.13288/j.11-2166/r.2025.07.015.
气管切开术后并发肉芽组织增生是临床常见并发症。经电子支气管镜治疗可短期缓解气道阻塞,但存在复发率高、远期预后不佳等问题。基于中医“窠囊”理论,结合现代病理机制,探讨其与气管切开术后肉芽增生的病机联系,并总结运用窠囊理论治疗气管切开术后并发肉芽组织增生的经验,认为本病病机以正气亏虚、脏腑功能失调为本,痰瘀互结为标。提出化痰活血、散结消积,宣达气机、疏壅通滞,固本培元、扶正祛邪的治疗思路,使痰瘀得化,窠囊消散,以达防治肉芽组织增生之效。
Granulation tissue hyperplasia after tracheotomy is a common clinical complication. Endoscopic treatment can temporarily relieve airway obstruction, however, it is associated with a high recurrence rate and poor long-term prognosis. Based on the traditional Chinese medicine (TCM)
Kenang
(窠囊) theory and combined with modern pathological mechanisms, this paper explores its correlation with the pathogenesis of post-tracheotomy granulation tissue hyperplasia. Drawing from clinical experience in applying the
Kenang
theory for treatment, this paper proposes that the fundamental pathogenesis of this condition lies in
qi
deficiency and organ dysfunction, while phlegm and blood stasis interlocking serve as the symptomatic manifestations. The treatment focuses on resolving phlegm and promoting blood circulation, dispersing nodules and eliminating stagnation, regulating
qi
flow, and reinforcing the body's vital energy while expelling pathogenic factors. This approach aims to dissolve phlegm and blood stasis, dissipate the
Kenang
, and ultimately prevent and treat granulation tissue hyperplasia.
WAIN JC . Postintubation tracheal stenosis [J]. Chest Surg Clin N Am , 2003 , 13 ( 2 ): 231 - 246 .
VARGAS M , BATTAGLINI D , ANTONELLI M , et al . Follow-up short and long-term mortalities of tracheostomized critically ill patients in an Italian multi-center observational study [J]. Sci Rep , 2024 , 14 ( 1 ): 2319 - 2327 .
DEMPSEY GA , BEN M , CLARE H , et al . Long-term outcome following tracheostomy in critical care: a systematic review [J]. Cri Care Med , 2016 , 44 ( 3 ): 617 - 628 .
MADU CN , MACHUZAK MS , STERMAN DH , et al . High-dose-rate (HDR) brachytherapy for the treatment of benign obstructive endobronchial granulation tissue [J]. Int J Radiat Oncol Biol Phys , 2006 , 66 ( 5 ): 1450 - 1456 .
TENDULKAR RD , FLEMING PA , REDDY CA , et al . High-dose-rate endobronchial brachytherapy for recurrent airway obstruction from hyperplastic granulation tissue [J]. Int J Radiat Oncol Biol Phys , 2008 , 70 ( 3 ): 701 - 706 .
PAPLA B , DYDUCH G , FRASIK W , et al . Post-intubation tracheal stenosis:morphological-clinical investigations [J]. Pol J Pathol , 2003 , 54 ( 4 ): 261 - 266 .
MARK EJ , MENG F , KRADIN RL , et al . Idiopathic tracheal stenosis: a clinicopathologic study of 63 cases and comparison of the pathology with chondromalacia [J]. Am J Surg Pathol , 2008 , 32 ( 8 ): 1138 - 1143 .
MEENAN K , BHATNAGAR K , GUARDIANI E . Intubation-related laryngeal pathology precluding tracheostomy decannulation: incidence and associated risk factors [J]. Ann Otol Rhinol Laryngol , 2021 , 130 ( 9 ): 1078 - 1084 .
孙淼 , 王玉艳 , 孟小钰 , 等 . 基于“肾虚、痰湿、血瘀”的现代生物学基础探讨PCOS中医病机的科学内涵 [J]. 时珍国医国药 , 2022 , 33 ( 6 ): 1412 - 1415 .
王科 , 晁生武 . 创面愈合相关机制的研究进展 [J]. 中华损伤与修复杂志 (电子版), 2021 , 16 ( 1 ): 81 - 84 .
岳慧娟 , 张培莉 , 庞敏 . 长期氧疗对肺部疾病防治作用的研究进展 [J]. 护理研究 , 2015 , 29 ( 35 ): 4365 - 4367 .
卢香琼 , 刘伟臣 , 秦艳 , 等 . 早期气管插管机械通气在老年颅脑外伤患者抢救中的意义 [J]. 中国老年学杂志 , 2022 , 42 ( 21 ): 5183 - 5185 .
王广发 , 黄珺君 , 章巍 . 成人诊断性可弯曲支气管镜检查术应用指南(2019年版) [J]. 中华结核和呼吸杂志 , 2019 , 42 ( 8 ): 573 - 590 .
0
浏览量
0
下载量
1
CSCD
关联资源
相关文章
相关作者
相关机构
京公网安备11010102007558号