1.中国中医科学院西苑医院国家中医心血管病临床医学研究中心,北京市海淀区西苑操场1号,100091
2.北京中医药大学研究生院
xuhaotcm@hotmail.com
收稿:2025-01-14,
修回:2025-05-18,
纸质出版:2025-08-17
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赵麟,丁姝辰,薛梅等.高血压慢病管理平台辅助中医综合降压方案治疗原发性高血压病的前瞻性队列研究[J].中医杂志,2025,66(16):1687-1694.
ZHAO Lin,DING Shuchen,XUE Mei,et al.Hypertension Chronic Disease Management Platform-Assisted Traditional Chinese Medicine Comprehensive Antihypertensive Regimen for the Treatment of Primary Hypertension: A Prospective Cohort Study[J].Journal of Traditional Chinese Medicine,2025,66(16):1687-1694.
赵麟,丁姝辰,薛梅等.高血压慢病管理平台辅助中医综合降压方案治疗原发性高血压病的前瞻性队列研究[J].中医杂志,2025,66(16):1687-1694. DOI: 10.13288/j.11-2166/r.2025.16.011.
ZHAO Lin,DING Shuchen,XUE Mei,et al.Hypertension Chronic Disease Management Platform-Assisted Traditional Chinese Medicine Comprehensive Antihypertensive Regimen for the Treatment of Primary Hypertension: A Prospective Cohort Study[J].Journal of Traditional Chinese Medicine,2025,66(16):1687-1694. DOI: 10.13288/j.11-2166/r.2025.16.011.
目的
2
观察高血压慢病管理平台辅助中医综合降压方案在真实世界中控制血压的效果,并评价患者对该方案的满意度。
方法
2
共纳入160例原发性高血压病患者,令患者使用高血压慢病管理平台进行自我管理并自主决定是否应用中医综合降压方案(包括降压八段锦、穴位按摩、中药代茶饮),1个月后调查患者血压变化情况、各治疗方案的应用率,通过Logistic回归分析各方案与血压变化的相关性,排除部分患有可能影响方案使用的共病患者进行敏感性分析,验证研究结果的可靠性,通过交互性分析探索各方案间是否存在协同作用,并调查患者满意度。
结果
2
最终纳入患者149例,与未规律使用中医综合降压方案的患者比较,规律使用中医综合降压方案的患者舒张压下降更为显著(
P
<0.05)。Logistic回归分析结果显示收缩压下降与使用中药汤剂相关,舒张压下降与使用中药汤剂、规律使用中医综合降压方案相关(
P
<0.05)。敏感性分析提示上述研究结果稳定。交互性分析结果显示,降压八段锦与穴位按摩、降压八段锦与中药代茶饮、穴位按摩与中药代茶饮对收缩压和舒张压的影响并无交互性作用(
P
>0.05)。130例(130/149,87.25%)患者认为高血压慢病管理平台有所帮助或帮助很大,111例(111/149,74.50%)患者认为中医综合降压方案有所帮助或帮助很大。
结论
2
规律使用中医综合降压方案有助于降低原发性高血压病患者舒张压水平,且患者对使用高血压慢病管理平台及中医综合降压方案有较高的满意度。
Objective
2
To observe the effect of the hypertension chronic disease management platform-assisted traditional Chinese medicine (TCM) comprehensive antihypertensive regimen on blood pressure control in the real world, and evaluate patients' satisfaction with this regimen.
Methods
2
A total of 160 patients with primary hypertension were recruited, and the patients were asked to use the hypertension chronic disease management platform for self-management and to decide whether to apply TCM comprehensive antihypertensive regimen (including Baduanjin for lowering blood pressure, acupoint massage, and Chinese medicinal tea). One month later, the changes in patients' blood pressure and the application rate of each treatment regimen were investigated. Logistic regression analysis was used to analyze the correlation between each regimen and blood pressure changes. Sensitivity analysis was performed by excluding some patients with comorbidities that might affect the use of the regimens to verify the reliability of the research results. Interaction analysis was conducted to explore whether there was a synergistic effect between the regimens, and patient satisfaction was also surveyed.
Results
2
A total of 149 patients were finally included. Compared with patients who did not use TCM comprehensive antihypertensive regimen regularly, those who used it regularly had a more significant decrease in diastolic blood pressure (
P
<0.05). The results of Logistic regression analysis showed that the decrease in systolic blood pressure was associated with the use of TCM decoctions, and the decrease in diastolic blood pressure was associated with the use of TCM decoctions and regular use of TCM comprehensive antihypertensive regimen (
P
<0.05). Sensitivity analysis suggested that the above research results were stable. The results of interaction analysis showed that there was no interactive effect between antihypertensive Baduanjin and acupoint massage, antihypertensive Baduanjin and Chinese medicinal tea, or acupoint massage and Chinese medicinal tea on systolic and diastolic blood pressure (
P
>0.05). One hundred and thirty patients (130/149, 87.25%) thought the hypertension chronic disease management platform was helpful or very helpful, and 111 patients (111/149, 74.50%) thought TCM comprehensive antihypertensive regimen was helpful or very helpful.
Conclusion
2
Regular use of TCM comprehensive antihypertensive regimen helps reduce the diastolic blood pressure level in patients with primary hypertension, and patients have a high degree of satisfaction with the use of the hypertension chronic disease management platform and TCM comprehensive antihypertensive regimen.
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