LI Jiaqi,HAN Wenzhao,YANG Qian,et al.Syndrome Differentiation and Treatment of Alopecia Areata Based on the Turbid Toxin Theory from the Perspectives of the Liver,Spleen,and Kidney[J].Journal of Traditional Chinese Medicine,2025,66(23):2494-2498.
LI Jiaqi,HAN Wenzhao,YANG Qian,et al.Syndrome Differentiation and Treatment of Alopecia Areata Based on the Turbid Toxin Theory from the Perspectives of the Liver,Spleen,and Kidney[J].Journal of Traditional Chinese Medicine,2025,66(23):2494-2498.DOI: 10.13288/j.11-2166/r.2025.23.016.
Alopecia areata (AA) is a common hair loss disorder, and the core pathogenesis is the internal gene-ration of turbid toxin caused by
qi
movement disorder in the liver, spleen, and kidney. Turbid toxin serves as both a pivotal etiological trigger and a pathological driver of disease exacerbation. Clinically, AA can be classified into four principal patterns, including liver constraint with spleen deficiency, internal accumulation of damp-heat, liver-kidney depletion, and
qi
-blood depletion. Therapeutic strategies prioritize clearing and resolving turbid toxin while regulating the
qi
movement of the liver, spleen, and kidney. Accordingly, different formulas were applied. Self-formulated
Shugan Jianpi Huazhuo Formula
(疏肝健脾化浊方) is suggested to drain dampness, resolve turbidity, and unblock
qi
movement. Self-formulated
Sanjiao Fenxiao Jiedu Formula
(三焦分消解毒方) can be used to clear heat, drain dampness and resolve to
xin. Self-formulated
Zishen Yanggan Toudu Decoction
(滋肾养肝透毒汤) can clear and vent latent toxins, while Self-formulated
Guiqi Shengfa Didu Formula
(归芪生发涤毒方) is employed to tonify
qi
and blood, purge toxins, and regenerate vitality. By differentiating and treating AA based on the functional patterns of the liver, spleen, and kidney, this approach expands the application scope of the turbid toxin theory and provides valuable insights for treatment of AA.
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references
TAN IJ , JAFFERANY M . Psychosocial impact of alopecia areata in paediatric and adolescent populations: a syste-matic review [J]. J Paediatr Child Health , 2024 , 60 ( 12 ): 778 - 782 .