1.中国中医科学院西苑医院,北京市海淀区西苑操场1号,100091
2.天津中医药大学
3.国家中医心血管病临床医学研究中心
通信作者:jianhuaffcn@263. net
收稿:2025-04-25,
修回:2025-10-10,
纸质出版:2025-12-17
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李兰兰,彭涵,高佳明等.从气运于脉、血行于脉、脉为枢机探析冠心病的动态病机[J].中医杂志,2025,66(24):2603-2607.
LI Lanlan,PENG Han,GAO Jiaming,et al.Discussion on the Dynamic Pathogenesis of Coronary Heart Disease from the Perspective of "Qi Transporting in the Vessels,Blood Flowing in the Vessels,and the Vessels are the Pivotal"[J].Journal of Traditional Chinese Medicine,2025,66(24):2603-2607.
李兰兰,彭涵,高佳明等.从气运于脉、血行于脉、脉为枢机探析冠心病的动态病机[J].中医杂志,2025,66(24):2603-2607. DOI: 10.13288/j.11-2166/r.2025.24.015.
LI Lanlan,PENG Han,GAO Jiaming,et al.Discussion on the Dynamic Pathogenesis of Coronary Heart Disease from the Perspective of "Qi Transporting in the Vessels,Blood Flowing in the Vessels,and the Vessels are the Pivotal"[J].Journal of Traditional Chinese Medicine,2025,66(24):2603-2607. DOI: 10.13288/j.11-2166/r.2025.24.015.
基于中医气血理论,构建“气运于脉、血行于脉、脉为枢机”三维动态病机模型,指出脉是气血运行的关键枢纽,通畅时维持生理功能,失于约束则致病。并阐释冠心病动态病机演变规律,即功能失调期,情志等诱因致气机失常,气血输布滞缓,引发冠心病早期症状,以功能性失调为主;结构损伤期,脉道枢机调控失司,气血壅滞,痰瘀积聚,导致脉道结构损伤,病情复杂;多器官受累期,脉道失枢,气血逆乱,累及多脏,出现全身系统衰竭,预后凶险。在治疗策略上,根据不同阶段特点,提出调气、畅脉、活血三位一体的治疗原则,功能失调期调气血复脉枢、结构损伤期通脉道护枢机、多器官受累期和脏腑救逆乱。
Based on the theory of
qi
and blood in traditional Chinese medicine, this paper innovatively put forward and constructed the three-dimensional dynamic disease mechanism model of "
qi
transportating in the vessels, blood flowing in the vessels, and the vessels as the pivot", which points out that the vessels are the key pivot for the transportation of
qi
and blood, when vessels are unobstructed, they maintain normal physiological functions; when vessels lose their regulatory role, diseases occur. This model also explains the law of dynamic pathogenesis evolution of coronary atherosclerotic heart disease (CAD), in which CAD is divided into three stages. At dysfunction stage, riggers such as emotional disturbance lead to abnormal
qi
movement, slowing down the distribution of
qi
and blood, and inducing early symptoms of CAD, which are mainly manifested as functional disorders. At structural damage stage, the pivot regulatory function of vessels is lost, resulting in stagnation of
qi
and blood, and accumulation of phlegm and blood stasis, which further causes structural damage to vessels, leading to a more complex condition. At multi-organ involvement stage, vessels fail to act as the pivot, causing disordered flow of
qi
and blood and involvement of multiple
zang
-
fu
organs, eventually leading to systemic failure with a poor prognosis. In terms of treatment strategies, based on the characteristics of different stages, a three-in-one therapeutic principle of "regulating
qi
, smoothing vessels, and activating blood" is proposed, so as to regulate
qi
and blood to restore the pivot function of vessels during dysfunctional stage, to unblock vessels and protect their pivot function during structural damage stage, and to harmonize
zang
-
fu
organs and correct the disordered
qi
and blood during multi-organ involvement stage.
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