JIA Zhenhua.Syndrome Differentiation and Treatment Patterns in Chronic Obstructive Pulmonary Disease Guided by the Theory of Lung Collateral Disease[J].Journal of Traditional Chinese Medicine,2026,67(07):736-740.
JIA Zhenhua.Syndrome Differentiation and Treatment Patterns in Chronic Obstructive Pulmonary Disease Guided by the Theory of Lung Collateral Disease[J].Journal of Traditional Chinese Medicine,2026,67(07):736-740.DOI: 10.13288/j.11-2166/r.2026.07.007.
This paper explores the transmission patterns of "
qi
collaterals-
qi
airways-blood (vessels) collaterals" in chronic obstructive pulmonary disease (COPD) based on the syndrome differentiation and treatment theory of lung collateral disease. Lung
qi
collaterals carry original
qi
, pectoral
qi
and defensive
qi
, primarily responsible for regulation and nourishment. The lung's airway serves as the pathway for the ascending and descending of
qi
. The lung's blood (vessel) collaterals circulate
ying
(营)-blood to nourish and infiltrate. Those three work synergistically to complete the core function of the lung, including governing
qi
, controlling respiration, and facilitating "
qi
exchange and blood transformation", with their functions converging in the "minute collateral-sweat pores". The occurrence and development of COPD follow the transmission pattern of "
qi
collaterals-
qi
airways-blood (vessels) collaterals". Initially, the condition is rooted in
qi
stagnation
caused by deficiency (pectoral
qi
deficiency and sink), which leads to airway obstruction and difficulty in ventilation. Ultimately, disorder of
qi
affects the function of blood, resulting in a state of vessel collaterals obstruction characterized as "phlegm complicated by blood stasis hindering
ZHOU-SUCKOW Z , DUERR J , HAGNER M , et al . Airway mucus, inflammation and remodeling: emerging links in the pathogenesis of chronic lung diseases [J]. Cell Tissue Res , 2017 , 367 ( 3 ): 537 - 550 .
KUME H , YAMADA R , SATO Y , et al . Airway smooth muscle regulated by oxidative stress in COPD [J]. Antioxidants (Basel) , 2023 , 12 ( 1 ): 142 .
UNDEM BJ , KOLLARIK M . The role of vagal afferent nerves in chronic obstructive pulmonary disease [J]. Proc Am Thorac Soc , 2005 , 2 ( 4 ): 355 - 360 .