中国人民解放军北部战区总医院,辽宁省沈阳市沈河区文化路83号,110000
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收稿:2025-09-24,
修回:2026-04-07,
录用:2026-04-02,
纸质出版:2026-05-17
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于丽,巩阳.基于“因加而发”论治放射性肠损伤[J].中医杂志,2026,67(10):1107-1110.
YU Li,GONG Yang.Treatment of Radiation-Induced Intestinal Injury Based on the Theory of "Onset Due to Compounding Factors"[J].Journal of Traditional Chinese Medicine,2026,67(10):1107-1110.
于丽,巩阳.基于“因加而发”论治放射性肠损伤[J].中医杂志,2026,67(10):1107-1110. DOI: 10.13288/j.11-2166/r.2026.10.013.
YU Li,GONG Yang.Treatment of Radiation-Induced Intestinal Injury Based on the Theory of "Onset Due to Compounding Factors"[J].Journal of Traditional Chinese Medicine,2026,67(10):1107-1110. DOI: 10.13288/j.11-2166/r.2026.10.013.
以《黄帝内经》中“因加而发”观点为指导,认为放射性肠损伤的基本病机为本元虚损、外感火热毒邪,乃故邪致虚未解,又外感新邪之火热毒邪,内外相因,因加而发。治疗当扶正祛邪、攻补兼施,拟定经验方护肠抗辐汤为主方进行分期辨治,急性期随症加减补虚清热、解毒固肠等品,慢性期随症加减温肾补脾、滋阴养血等品,为放射性肠损伤的治疗提供思路。
Guided by the concept of "onset due to compounding factors" from
Inner Canon of Yellow Emperor
(《黄帝内经》), it is believed that the basic pathogenesis of radiation-induced intestinal injury is the depletion of the root and the
invasion of external pathogenic fire and heat toxin. The deficiency induced by pre-existing pathogen has not been resolved, and the external invasion of a new pathogen, characterized by fire and heat toxin, has further aggravated the condition, leading to radiation-induced intestinal injury due to the interaction of internal and external factors. The treatment should focus on reinforcing healthy
qi
and expelling pathogen, performingtreatment with both attack and supplementation. The experience-based prescription
Huchang Kangfu Decoction
(护肠抗辐汤) should be used as the main formula, with treatment differentiated according to stages. During the acute stage, adjustments on medicinals should be made to supplement deficiency, clear heat, resolve toxin, and consolidate the intestines. During the chronic stage, medicinals that can warm the kidneys, tonify the spleen, nourish the blood, and soften the liver should be modified according to symptoms. Above methods provide a treatment approach for radiation-induced intestinal injury.
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