Based on the typical cases from

Case Records as a Guide to Clinical Practice

（《临证指南医案》） where YE Tianshi applied the "morning and evening differential treatment"， the main types are summarized as follows. When there is middle-lower interlocking injury， and

yin

deficiency with wind stirring， the method of restraining and consolidating in the morning can be used to restrict

jueyang

（厥阳）. For deficiency of the extraordinary vessels and heart-spleen

ying

（营） impairment， the method of consolidating should be used to raise

yang

in the morning， while the method of moistening and nourishing

ying

-

yin

in the evening is used. For lower

jiao

（焦） depletion with phlegm turbidity obstructing the orifices， it is recommended to tonify lower

jiao

in the morning and fortify spleen and dissolve phlegm in the evening. If there is kidney-

yin

depletion with dampness obstructing the

qi

， it is suggested to supplement kidney and improve

qi

reception in the morning， while purify upper

jiao

in the evening. For deficiency and impairment of the collateral vessels， the method of moistening and nourishing

ying

-

yin

in the evening can be used. For heart-spleen

qi

knot， it is recommended to dissolve phlegm and dispel stasis in the evening. In cl

inical practice， the same medicinal formula can be used with different methods which change according to the syndrome. Taking

Sishen Pills

（四神丸） and

Yuhu Elixir

（玉壶丹） as examples， employing different methods in accordance with the primary and secondary pathomechanisms can help transform complex， multiple pathomechanisms into organized treatment steps， providing ideas for managing complicated syndromes with modern Chinese medicine in clinical practice.