1.河南中医药大学第一附属医院,河南省郑州市金水区人民路19号,450003
2.河南中医药大学第一临床医学院
3.河南中医药大学呼吸疾病中医药防治省部共建协同创新中心
4.河南省呼吸疾病循证评价国际联合实验室
5.英国利物浦热带医学院全球健康试验中心
li_js8@163.com
收稿:2026-01-20,
修回:2026-04-30,
录用:2026-04-25,
纸质出版:2026-06-17
移动端阅览
徐百川,谢洋,李艺婷等.中医药防治慢性阻塞性肺疾病前期的策略与实践[J].中医杂志,2026,67(12):1284-1288.
XU Baichuan,XIE Yang,LI Yiting,et al.Strategy and Practice of Traditional Chinese Medicine in Prevention and Treatment of Pre-Chronic Obstructive Pulmonary Disease[J].Journal of Traditional Chinese Medicine,2026,67(12):1284-1288.
徐百川,谢洋,李艺婷等.中医药防治慢性阻塞性肺疾病前期的策略与实践[J].中医杂志,2026,67(12):1284-1288. DOI: 10.13288/j.11-2166/r.2026.12.008.
XU Baichuan,XIE Yang,LI Yiting,et al.Strategy and Practice of Traditional Chinese Medicine in Prevention and Treatment of Pre-Chronic Obstructive Pulmonary Disease[J].Journal of Traditional Chinese Medicine,2026,67(12):1284-1288. DOI: 10.13288/j.11-2166/r.2026.12.008.
通过系统梳理慢性阻塞性肺疾病前期(pre-COPD)的概念演变与中医研究现状,并结合临床实践,提出中医药防治pre-COPD的策略,即应结合中医证候和体质辨识,识别高危人群;倡导治未病,辨证辨体相结合,实现个体化干预;中西医协同,依托数智技术,构建“医院-社区-家庭”全程管理模式。旨在实现pre-COPD人群早期诊断、早期干预与全程管理,以期为降低慢性阻塞性肺疾病(COPD)发病率提供助力。
By systematically reviewing the concept evolution of pre-chronic obstructive pulmonary disease (pre-COPD) and the research status of traditional Chinese medicine (TCM), as well as considering the clinical practice, this paper puts forward the strategies for the prevention and treatment of pre-COPD with TCM. These strategies include identifying high-risk groups by combining TCM syndrome and constitution, advocating the principle of "treating disease before it arises" and promoting the combination of syndrome differentiation and constitution evaluation to achieve individualized intervention, promoting collaboration between TCM and western medicine, supported by digital and intelligent technologies, to establish a whole-process management mode of "hospital-community-family". The aim is to realize the early diagnosis, early intervention and whole-process management of pre-COPD, thereby helping reduce the incidence of COPD.
The Global Initiative for Chronic Obstructive Lung Disease . Global strategy for prevention,diagnosis and management of COPD:2026 report [EB/OL]. ( 2025-11-17 )[ 2025-12-20 ]. https://goldcopd.org/2026-gold-report-and-pocket-guide/ https://goldcopd.org/2026-gold-report-and-pocket-guide/ .
HAN M K , AGUSTI A , CELLI B R , et al . From GOLD 0 to pre-COPD [J]. Am J Respir Crit Care Med , 2021 , 203 ( 4 ): 414 - 423 .
MARTINEZ F J , AGUSTI A , CELLI B R , et al . Treatment trials in young patients with chronic obstructive pulmonary disease and pre-chronic obstructive pulmonary disease patients: time to move forward [J]. Am J Respir Crit Care Med , 2022 , 205 ( 3 ): 275 - 287 .
YANG W , LI F , LI C , et al . Focus on early COPD: definition and early lung development [J]. Int J Chron Obstruct Pulmon Dis , 2021 , 16 : 3217 - 3228 . doi: 10. 2147/COPD.S338359 http://dx.doi.org/10.2147/COPD.S338359 .
PAUWELS R A , BUIST A S , CALVERLEY P M , et al . Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease. NHLBI/WHO Global Initiative for Chronic Obstructive Lung Disease (GOLD) Workshop summary [J]. Am J Respir Crit Care Med , 2001 , 163 ( 5 ): 1256 - 1276 .
VESTBO J , LANGE P . Can GOLD Stage 0 provide information of prognostic value in chronic obstructive pulmonary disease? [J] Am J Respir Crit Care Med , 2002 , 166 ( 3 ): 329 - 332 .
RABE K F , HURD S , ANZUETO A , et al . Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease: GOLD executive summary [J]. Am J Respir Crit Care Med , 2007 , 176 ( 6 ): 532 - 555 .
WAN E S , HOKANSON J E , MURPHY J R , et al . Clinical and radiographic predictors of GOLD-unclassified smokers in the COPD gene study [J]. Am J Respir Crit Care Med , 2011 , 184 ( 1 ): 57 - 63 .
Global Initiative for Chronic Obstructive Lung Disease . Global strategy for the diagnosis, management, and Prevention of chronic obstructive pulmonary disease: 2022 report [EB/OL]. ( 2021-11-15 ) [ 2025-12-20 ]. https://goldcopd.org/2022-gold-reports/ https://goldcopd.org/2022-gold-reports/ .
VENKATESAN P . GOLD COPD report: 2023 update [J]. Lancet Respir Med , 2023 , 11 ( 1 ): 18 .
刘耘充 , 王红梅 , 郑丹蕾 , 等 . 早期慢性阻塞性肺疾病诊断及治疗进展与争议 [J]. 中华医学杂志 , 2021 , 101 ( 2 ): 159 - 164 .
LI W , LEI J , LI B , et al . Lung Health of Early COPD (LHEC): a multi-center cohort study-rational and design [J]. Int J Chron Obstruct Pulmon Dis , 2025 , 20 : 2561 - 2568 . doi: 10.2147/COPD.S517185 http://dx.doi.org/10.2147/COPD.S517185 .
HAN M K , YE W , WANG D , et al . Bronchodilators in tobacco-exposed persons with symptoms and preserved lung function [J]. N Engl J Med , 2022 , 387 ( 13 ): 1173 - 1184 .
THAMRIN C , MARTIN A , BADAL T , et al . Dual bronchodilator treatment for prevention of COPD in at-risk smokers [J]. Respirplogy , 2022 , 27 ( 11 ): 983 - 986 .
BUI D S , FANER R , WASHKO G , et al . pre-COPD: an evolving concept with practice potential [J]. Lancet Respir Med , 2025 , 13 ( 9 ): 778 - 781 .
DHARMAGE S C , FANER R , Agustí A . Treatable traits in pre-COPD: time to extend the treatable traits paradigm beyond established disease [J]. Respirplogy , 2024 , 29 ( 7 ): 551 - 562 .
吴繁 , 邓志珊 , 田禾燊 , 等 . 慢性阻塞性肺疾病前期的研究进展 [J]. 中华结核和呼吸杂志 , 2023 , 46 ( 10 ): 1028 - 1034 .
LI J , XIE Y , WANG M , et al . Effect of traditional Chinese medicine combined with conventional western medicine for patients with severe/very severe chronic obstructive pulmonary disease: a multi-center, randomized, double-blind, controlled study [J]. Chin Med , 2025 , 20 ( 1 ): 66 .
LI J , WANG M , XIE Y , et al . A randomized, double-blinded, placebo-controlled study of the use of traditional Chinese medicine for treating patients with mild/moderate chronic obstructive pulmonary disease [J]. J Evid Based Med , 2025 , 18 ( 2 ): e70023 .
LI J , XIE Y , WANG Y , et al . Effect of acupuncture on patients with chronic obstructive pulmonary disease: a multicenter randomized controlled trial [J]. Complement Ther Med , 2025 , 89 : 103146 . doi: 10.1016/j.ctim. 2025.103146 http://dx.doi.org/10.1016/j.ctim.2025.103146 .
LI J , CHEN R , YU X , et al . Guidelines of integrated Chinese and western medicine for diagnosis and treatment of chronic obstructive pulmonary disease (2022) [J]. J Evid Based Med , 2023 , 16 ( 4 ): 565 - 580 .
李建生 . 慢性阻塞性肺疾病中医康复指南 [J]. 世界中医药 , 2020 , 15 ( 23 ): 3710 - 3718 .
方旖旎 , 王琦 , 张国辉 , 等 . 中医体质学在“治未病”中的应用研究 [J]. 中医杂志 , 2020 , 61 ( 7 ): 581 - 585 .
ÇOLAK Y , AFZAL S , NORDESTGAARD B G , et al . Prognosis of asymptomatic and symptomatic, undiagnosed COPD in the general population in Denmark: a prospective cohort study [J]. Lancet Respir Med , 2017 , 5 ( 5 ): 426 - 434 .
柳月 , 袁媛 . 慢性阻塞性肺疾病筛查工具准确性的网状Meta分析 [J]. 中国全科医学 , 2022 , 25 ( 35 ): 4443 - 4452 .
WU F , ZHOU Y , PENG J , et al . Rationale and design of the early chronic obstructive pulmonary disease (ECOPD) study in Guangdong, China: a prospective observational cohort study [J]. J Thorac Dis , 2021 , 13 ( 12 ): 6924 - 6935 .
ADELOYE D , SONG P , ZHU Y , et al . Global, regional, and national prevalence of, and risk factors for, chronic obstructive pulmonary disease (COPD) in 2019: a systematic review and modelling analysis [J]. Lancet Respir Med , 2022 , 10 ( 5 ): 447 - 458 .
龚海英 , 陈涤平 . 中医“治未病”与“未病状态”辨识 [J]. 中医杂志 , 2020 , 61 ( 10 ): 913 - 916 .
谢永霞 , 王佳佳 , 冯贞贞 , 等 . 2011—2022年慢性阻塞性肺疾病急性加重期证候学研究述评 [J]. 中医杂志 , 2023 , 64 ( 23 ): 2382 - 2387 .
李静 , 王艳红 , 孙美香 , 等 . 舒肺贴用于慢性阻塞性肺疾病急性加重期患者中的效果及对生存质量的影响 [J]. 临床医学研究与实践 , 2025 , 10 ( 34 ): 126 - 129 .
SUN J , ZHANG D , WANG P , et al . Potential active ingredients and mechanisms of Shufeitie ointment in the treatment of chronic obstructive pulmonary disease by integrating transdermal chemistry and network pharmacology [J]. Front Med (Lausanne) , 2025 , 12 : 1605372 . doi: 10.3389/fmed.2025.1605372 http://dx.doi.org/10.3389/fmed.2025.1605372 .
LIN X , XU Q , XU W , et al . Comparative efficacy of different traditional mind-body exercises in patients with stable chronic obstructive pulmonary disease: a syste-matic review and network meta-analysis [J]. Front Med (Lausanne) , 2025 , 12 : 1678352 . doi: 10.3389/fmed. 2025.1678352 http://dx.doi.org/10.3389/fmed.2025.1678352 .
SUJIE M , KAIWEN X , HONG X , et al . The impact of traditional mind-body exercises on pulmonary function, exercise capacity, and quality of life in patients with chronic obstructive pulmonary disease: a systematic review and meta-analysis of randomized controlled trials [J]. Front Med (Lausanne) , 2024 , 11 : 1359347 . doi: 10.3389/fmed.2024.1359347 http://dx.doi.org/10.3389/fmed.2024.1359347 .
WU D , LIU W , WANG J , et al . Clinical application guideline of combination with traditional Chinese medicine and Western medicine in the prevention and treatment of chronic obstructive pulmonary disease (2024) [J]. J Evid Based Med , 2025 , 18 ( 2 ): e70024 .
XIE Y , LI Y , ZHANG P , et al . Effectiveness and safety of Bufei granules in treatment of preserved ratio impaired spirometry: study protocol for a randomized controlled trial [J]. Eur J Integr Med , 2025 , 102580 . doi: 10. 2147/COPD.S517185 http://dx.doi.org/10.2147/COPD.S517185 .
韩雪 , 王斌全 , 安俊红 , 等 . COPD病人医院-社区-家庭-个人管理模式研究进展 [J]. 护理研究 , 2021 , 35 ( 4 ): 682 - 684 .
0
浏览量
0
下载量
0
CSCD
关联资源
相关文章
相关作者
相关机构
京公网安备11010102007558号