The experience on a case of human allogeneic orthotopic transplantation of liver with acute rejection reaction treated with differentiation of syndrome was reported. The principles of clearing heat

eliminatingdampness

detoxification and eliminating filth

soothing and dredging liverand bile

facilitating bile duct. Immune depressing method was also used so that the primary rejection reaction was rapidly brought undercontrol and reversed. Then phlegm and blood stasis were treated at thesame time with facilitating the flowing of bile

so that the remained jaundice can be also cured and liver function recovered.