Self - control method was adopted with a dosage of 2 - 4 capsule q. d. or b. i. d. for a course of 8 weeks. Results showed that 9 clinical indices of the 12 had obvious amelioration before and after treatment （P<0. 01）

while the other 3 indices

viz. the occipital -parietal distance

digital -ground distance

schober test didn’t have improvement before and after the treatment （P>0. 05）. In the 12 lab indices

only platelets

ESR

γ -globulin

revealed stalistical significance before and after the treatment （P < 0. 01）. 5 cases were clinically cured （6.94%）

31 （43.06%） markedly effective

36 cases （50. 0%） effective

the total effective rate being 100%. Experiments showed that Puduluo capsule in different dosages revealed very significant ami -inflammatory

analgesic actions in arthritis mice models

and

obviously inhibited the cellular immune function. It regulated biphasically the immunity in human body

lowered CD4/CD8 ratio. The analgesic and anti - inflammatory action was greater than that in the positive control group treated with indomethacin.