Sixty cases of chronic pulmonary heart disease at acute attack stage in the treatment group and 60 cases of the control group were treated with oxygen - inspiration

relieving spasm and asthma

anti - infection

and correcting respiratory failure and heart failure as basic treatment. Self - made Chinese drug Fei Xin Ning Mixture was added to the treatment group. In the two groups. 15 days constituted one course. Plasma endothelin 1 （ET-1） level and hernorheologic indices were determined before and after treatment. Results indicated that the markedly effective rate

effectice rate and the total effective rate in the treatment group were 73. 33%. 20% and 93. 34% respectively

and 35%

33. 34% and 68. 34% in the control group

with significant difference in the total effective rate between the two groups <P<.0. 01). Plasma endothelin -1 level after treatment in the treatment group was significantly lower than that in the control group （P <0. 01）

and the hetnorheologie indices in the treatment group decreased significantly as compared with those before treatment or after treatment in the control group （P<0. 05 or P<0. 01）. It is suggested that Fei Xin Ning Mixture can obviously increase the total effective rate and decrease plasma endothelin - 1 level and improve blood rheology for chronic pulmonary heart disease at acute attack stage

and it has a better therapeutic effect than that of the simple Western medicine treatment.