To explore the effect of acupuncture at Neiguan （PC 6） on the cardiovascular functions in the patient with low pulse pressure syndrome. Methods: 49 cases were randomly divided into acupuncture group and medicine group. Acupuncture group was treated by acupuncture at bilateral Neiguan （PC 6） for 3 consecutive days

and the medicine group was given intravenous drip of Shenmai Injectio for 6 consecutive days. 20ml each day. Blood pressure

pulse pressure. SV

CO. LVWL

MAP

TPR. CCP

PAWP

BV

MHR and CMBV were examined before and after treatment. 23 healthy subjects were observed as controls. Results: The pulse pressure of patients before treatment was significantly lower than that of controls （P<0. 01）

and after treatment it was raised (P<0.01.SV

CO. LVWL. PAWP

BV. MHR and CMBV of patient were significantly lower than those of healthy subjects （P<0. 01）

but after treatment they raised in both groups （P<0. 01）. CCP and TPR of patients before treatment were significantly higher than those of healthy subjects （P<0. 01）

and after treatment decreased significantly （P<0. 01）. The therapeutic effect of acupuncture treatment was slightly better than that of medicine group （P<0. 05 for part of the indexes）. There was no significant difference in MAP between the two groups. Conclusion: Acupuncture at Neiguan （PC 6） can strengthen pumping blood function of the heart. decrease the peripheral resistance. improve microcirculation and increase difference of pulse pressure.