Zhao JingxiangSchool Hospital of Shandong College of Architectural Engineering. Jinan 250014. Shandong Province.. Effects of Xiaoyao Pills on Lipoprotein. Apoproteins and Hemorheologic Indexes in the Patient of Ischemic Cerebrovascular Disease at Restoration Stage[J]. Journal of Traditional Chinese Medicine2003, (7): 510-511.
Zhao JingxiangSchool Hospital of Shandong College of Architectural Engineering. Jinan 250014. Shandong Province.. Effects of Xiaoyao Pills on Lipoprotein. Apoproteins and Hemorheologic Indexes in the Patient of Ischemic Cerebrovascular Disease at Restoration Stage[J]. Journal of Traditional Chinese Medicine2003, (7): 510-511.DOI: 10.13288/j.11-2166/r.2003.07.022.
Objective: To observe effects of Xiaoyao Pills on lipoprotein. apoprotein and hemorheologic indexes in the patient of ischemic cerebrovascular disease at restoration stage. Methods: 126 cases of ischemic cerebrovascular disease at restoration stage were randomly divided into treatment group (n=68) treated with oral administration of Xiaoyao Pills. 9g each time
thrice daily
and control group (n = 58) treated with oral administration of total saponin of Gynostemma pentaphyllum. 2 tablets each time
thrice daily
with a therapeutic course of 2 months. Changes of lipoprotein
apoprotein and hemorheologic indexes before and after treatment were investigated. Results: After treatment
in treatment group
triglyceride (TG)
total cholesterol (TO . low density lipoprotein cholesterol (LDL-C). very low density lipoprotein cholesterol (VLDL-C) and apoprotein B100 (ApoB-100) levels were significantly decreased (P<0. 01). and high density lipoproteincholesterol (HDL-C) and apoprotein A- I (ApoA- 1 ) levels were significantly increased (P < 0. 01). hemorheologic indexes significantly improved (P < 0. 01). In decrease of TG. TC. LDL-C. ApoB-100. increase of HDL-C. and ApoA- I levels. and improvement of hemorheologic indexes
treatment group was superior to control group (P< 0.01). Conclusion: Xiaoyao Pills can effectively inhibit abnormal metabolism of lipoprotein and hyperviscositemia in the patient of ischemic cerebrovascular disease at restoration stage
so as to play active role in rehabilitation treatment and prevention of secondary recurrence.