Objective: To assess clinical therapeutic effect of Ziyin Xifeng Huoxue Decoction on Parkinson’s disease at early stage. Methods: 40 patients under basic therapy were randomly divided into treatment and control group. 20 cases in each. Treatment group were treated with Ziyin Xifenng Huoxue Decoction and the control group were treated with Madopa tablets for 3 months. TCM senile tremor syndrome dysfunction scores and changes UPDRS scores were evaluated. Results: After treatment

there were no significant differences in senile tremor syndrome dysfunction scores and UPDRS scores between two groups （P>0. 05）. but there were significant differences before and after treatment in the two groups （both P<0. 01）. After treatment of 3 months

the total markedly effective rate was 40% and the total effective rate was 80% for the change of UPDRS scores with no significant difference as compared with the control group. Conclusion: Ziyin Xifeng Huoxue Decoction has obvious therapeutic effect on Parkinson’s disease at early stage.