Objective: To observe therapeutic effect of Qingliang Huoxue Yin on retinal vein obstruction（RVO） of blood heat stagnation type. Methods: The patients of RVO were definitely diagnosed by fundus fluorescein angiography（FFA）. Among them

the patients of blood heat stagnation type were randomly divided into a treatment group（n=68） treated by self-stipulated Qingliang Huoxue Yin and a control group（n=30） treated by intravenous drip of Mailuoning. Clinical therapeutic effects of the two groups and changes of hemorhologic indexes

and plasma tissue type plasminogen activator （T-PA） and plasminogen activator inhibitor（PAl） activities after treatment in the treatment group were investigated. Results: The total effective rate was 80.9% in the treatment group. superior to the control group （P<0.05）

and after treatment the hemorhelogic indexes improved and plasma T-PA increased and PAI decreased significantly in the treatment group

superior to that before treatment （P<0.01）. Conclusion: Qingliang Huoxue Yin has a better therapeutic effects for the patient of RVO of blood heat stagnation type.