Peng Bo. Effects of Ganlan Jiejiu Yin on ALT and AST in Rats and Mice with Acute Alcoholic Hepatic Injury[J]. Journal of Traditional Chinese Medicine2004, (10): 774-776.
Peng Bo. Effects of Ganlan Jiejiu Yin on ALT and AST in Rats and Mice with Acute Alcoholic Hepatic Injury[J]. Journal of Traditional Chinese Medicine2004, (10): 774-776.DOI: 10.13288/j.11-2166/r.2004.10.036.
Objective: To observe preventive and therapeutic effects of Ganlan Jiejiu Yin on acute alcoholic hepatic injury in the rat and the mouse
and to study preliminarily effects on alinine transaminase(ALT) and aspartic transaminase (AST) in serum and hepatic homogenate. Methods: The acute alcoholic hepatic injury model was made by stomach perfusion of white spirit for 5 days
and drunk time and the recovering time were observed every day
and serum ALT on the 3rd day and ALT and AST in serum and hepatic homogenate on the 5th day were determined
and the results were compared with those of Hugan Capsules. Results: Ganlan Jiejiu Yin could significantly decrease the drunk rate
increase the recovery/drunk ratio
and decrease ALT and AST in serum and ALT in hepatic homogenate with significant differences as compared with those of the control group. Conclusion: Ganlan Jiejiu Yin has good drunk-preventing
alcoholism-relieving and liver-protecting actions.