肝癌患者中医辨证分型与肝癌细胞体外化疗药物敏感性的关系

皇甫超申; 刘彬; 李鲁娟; 殷明伟; 陈传波

doi:10.13288/j.11-2166/r.2005.01.028

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肝癌患者中医辨证分型与肝癌细胞体外化疗药物敏感性的关系

更新时间：2021-11-20

- 肝癌患者中医辨证分型与肝癌细胞体外化疗药物敏感性的关系
- Relation of TCM Syndrome Types of the Patient of Liver Cancer with Sensitivity of Liver Cancer Cells to Chemotherapeutic Drugs in Vitro
- 中医杂志 2005年第1期页码：50-51
- 作者机构：
  
  1. 河南大学医学院消化疾病研究所
  2. 河南大学第一附属医院
  3. 河南大学第一附属医院河南省开封市西门大街356号,475001
- 作者简介：
- 基金信息：
  
  河南省2002年科技攻关项目（124170229）
- DOI：10.13288/j.11-2166/r.2005.01.028
  中图分类号： R273
- 纸质出版：2005
- 稿件说明：
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[1]皇甫超申,刘彬,李鲁娟,殷明伟,陈传波.肝癌患者中医辨证分型与肝癌细胞体外化疗药物敏感性的关系[J].中医杂志,2005(01):50-51.

Relation of TCM Syndrome Types of the Patient of Liver Cancer with Sensitivity of Liver Cancer Cells to Chemotherapeutic Drugs in Vitro[J]. Journal of Traditional Chinese Medicine2005, (1): 50-51.
[1]皇甫超申,刘彬,李鲁娟,殷明伟,陈传波.肝癌患者中医辨证分型与肝癌细胞体外化疗药物敏感性的关系[J].中医杂志,2005(01):50-51. DOI： 10.13288/j.11-2166/r.2005.01.028.

Relation of TCM Syndrome Types of the Patient of Liver Cancer with Sensitivity of Liver Cancer Cells to Chemotherapeutic Drugs in Vitro[J]. Journal of Traditional Chinese Medicine2005, (1): 50-51. DOI： 10.13288/j.11-2166/r.2005.01.028.

摘要

目的:观察不同中医辨证分型肝癌患者肝癌细胞体外化疗药物敏感性。方法:选取60例肝癌切除标本

利用 MTT 法测定不同证型肝癌患者对6种常用化疗药物的体外敏感性。结果:脾气虚组、肝气郁结组、瘀血阻络组之间各药敏感性有逐步下降趋势

但无统计学意义;各药在肝瘀脾虚阻络组敏感性明显下降。结论:不同中医辨证分型肝癌患者对化疗药物的敏感性存在一定差异

中西医结合个体化治疗肝癌

就是要根据具体患者药敏实验结果结合辨证论治设计治疗方案。

Abstract

Objective:To observe sensitivity of liver cancer cells of the patient of liver cancer with different TCM syndromes to chemotherapeutic drugs in vitro.Methods:60 specimens from removed liver cancer were taken and the sensitivity of the hepatic cells from patients of live cancer with different TCM syndromes to 6 commonly-used chemotherapeutic drugs in vitro were determined by MTT method.Results:The sensitivity to the drugs in the deficiency of the spleen Qi-deficiency group

the liver-Qi stagnation group and the group of obstruction of blood stasis in collaterals had the tendency to gradually decrease with no statistically significant difference;the sensitivity to various drugs in the groups of stasis of blood in the liver.deficiency of the spleen and obstruction in collateral decreased significantly.Conclusion:The patients of liver cancer with different TCM syndromes have a certain difference in the sensitivity to chemotherapeutic drugs

so treatment of liver cancer should be based on the patients’ sensitivity to therapeutic drugs and TCM syndromes.

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