补益阳明津气对初老雌性大鼠卵巢流式细胞双标百分比的影响

李燕; 郭蓉晓; 吴涢; 周淑芳; 谭万信

doi:10.13288/j.11-2166/r.2005.12.038

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补益阳明津气对初老雌性大鼠卵巢流式细胞双标百分比的影响

更新时间：2021-11-20

- 补益阳明津气对初老雌性大鼠卵巢流式细胞双标百分比的影响
- Effect of Replenishing Functional Activities of the Body Fl■ of The Yangming Channel on Double-Labeling Percentage of Ovary Flowcytes in the Initial Aging Female Rats
- 中医杂志 2005年第12期页码：937-939
- 作者机构：
  
  1. 贵阳中医学院妇科教研室
  2. 成都中医药大学附属医院
  3. 成都中医药大学2002级
  4. 成都中医药大学贵州省贵阳市市东路50号,550002
  5. 博士研究生
- 作者简介：
- 基金信息：
  
  国家自然科学基金项目（30371795）
- DOI：10.13288/j.11-2166/r.2005.12.038
  中图分类号： R285.5
- 纸质出版：2005
- 稿件说明：
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[1]李燕,郭蓉晓,吴涢,周淑芳,谭万信.补益阳明津气对初老雌性大鼠卵巢流式细胞双标百分比的影响[J].中医杂志,2005(12):937-939.

Effect of Replenishing Functional Activities of the Body Fl■ of The Yangming Channel on Double-Labeling Percentage of Ovary Flowcytes in the Initial Aging Female Rats[J]. Journal of Traditional Chinese Medicine2005, (12): 937-939.
[1]李燕,郭蓉晓,吴涢,周淑芳,谭万信.补益阳明津气对初老雌性大鼠卵巢流式细胞双标百分比的影响[J].中医杂志,2005(12):937-939. DOI： 10.13288/j.11-2166/r.2005.12.038.

Effect of Replenishing Functional Activities of the Body Fl■ of The Yangming Channel on Double-Labeling Percentage of Ovary Flowcytes in the Initial Aging Female Rats[J]. Journal of Traditional Chinese Medicine2005, (12): 937-939. DOI： 10.13288/j.11-2166/r.2005.12.038.

摘要

目的:探讨“补益阳明津气”延缓初老雌性大鼠卵巢机（?）老的机理。为促进绝经前期妇女健康

延缓绝经前期卵巢机能衰老

防治相关病证

提供一种新的研究与论治思路

并为（?）相关方药提供药效学依据。方法:4～6月龄雌性大鼠为正常对照组;10～12月龄

阴道细胞学表现动情期延长的雌性大鼠（?）为被老大鼠模型。模型动物随机分为益胃汤高剂量组、益胃汤中剂量组、益胃汤低剂量组、己烯雌酚组、模型对照组、六味地（?）组;灌药4周后

断头处死

取左侧卵巢检测卵巢流式细胞双标百分比。结果:与模型对照组比较

益胃汤可使卵巢流式细（?）标百分比降低。结论:实验研究提示

益胃汤具有抑制卵巢细胞凋亡的作用

这可能是其延缓卵巢机能衰老的机理之一。

Abstract

Objective:To probe into the mechanism of replenishing functio tivities of the body fluid of the Yangming Channel in delaying functional aging of ovary in the initial aging female rats.M:Female rats aged 4-6 months were used as normal control group

and the female rats aged 10-12 months with prolongation of estrus examined by colpocytology were used as the initial aging model.The model animals were randomly divided into 6 gro high dose Yiwei Decoction group

mid dose Yiwei Decoction group

low dose Yiwei Decoction group

diethylstilbestrol gro model control group

and Liuwei Dihuang Bolus group.After administration for 4 weeks

they were killed by decapitation

ft ovary was taken for detection of double-labeling percent of flowcytes of the ovary.Results:The double-labeling percent wcytes of the ovary decreased as compared with the model control group.Conclusion:The Yiwei Decoction has functio inhibiting apoptosis of ovary

which is possibly one of the mechanisms in delaying functional aging of the ovary.

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