Objective:To observe the therapeutic effect of Zhuang’er Granules on infantile recurrent respiratory tract infection with syndrome of qi and Yin deficiency.Methods:Eighty-six children of recurrent respiratory tract infection with syndrome of both qi and Yin deficiency were randomly divided into two groups

a treatment group treated by Zhuang’er Granules and a control group by Kamanshu oral liquor.They were treated for one month and then followed up for 6 months.Recurrent times

clinical main symptoms

T cell subpopulation

immunoglobulins and complement-3（C

3

） were determined before and after treatment.Results:The total effective rate in the treatment group（90.0%） was significantly higher than 80.6% in the control group（P

<

0.05）.After treatment

improvement of symptoms in the treatment group was better than in the control group（P

<

0.05）.CD

4

CD

8

CD

4

/CD

8

IgA

IgG and C

3

significantly increased in both groups

with significant differences as compared with those before treatment（P

<

0.05 or P

<

0.01）.Conclusion:Zhuang’er Granules is an effective prescription for treatment of infantile recurrent respiratory tract infection with syndrome of both qi and Yin deficiency.