HU Yonghe. Clinical Observation on the Effect of Wentang Granule for Impaired Glucose Tolerance——A Report of 48 Cases[J]. Journal of Traditional Chinese Medicine2009, 50(7): 609-612.
HU Yonghe. Clinical Observation on the Effect of Wentang Granule for Impaired Glucose Tolerance——A Report of 48 Cases[J]. Journal of Traditional Chinese Medicine2009, 50(7): 609-612.DOI: 10.13288/j.11-2166/r.2009.07.019.
Objective To study the effect of Wentang Granule(Granule for Stabilizing Glucose) on impaired glucose tolerance(IGT) of type Ⅱ diabetes.Methods Totally 150 patients with diagnosis of IGT were randomly divided into 3 groups:education group
observation group
and control group
with 50 cases in each.They were treated with guidance on life style
Wentang Granule
and Acarbose respectively and observed for 2 years.The observed indexes included fasting blood glucose(FBG)
serum lipid
body mass index(BMI)
waist hip ratio(WHR)
changes of TCM symptoms and scores.The therapeutic effect was evaluated with the changes of glucose tolerance.Results After treatment
the conversion rate of normal glucose tolerance and diabetes of the observation group and control groups was significantly different from that of the education group(P <0.05 or P<0.01).In the observation group
the FBG
serum lipid
BMI
WHR
TCM symptoms and scores were significantly different from those before treatment and those of the education group after treatment(P <0.05 or P<0.01).And the triglyceride(TG)
high density lipoprotein cholesterol(HDL-C)
and TCM symptoms and scores were significantly different from those of the control group after treatment(P <0.05 or P<0.01).Conclusion Wentang Granule can control carbohydrate and lipid metabolism to relieve symptoms
and can reduce the incidence of conversion of IGT to diabetes type Ⅱ.