Objective To research the characteristics of sex hormones and exfoliated cell of tongue fur in qi stagnation constitution during the perimenopause and provide help for the early identification.Methods Totally 180 women of mild constitution and qi stagnation constitution were selected and divided into premenopause

early menopausal transition and late menopausal transition according to the menstruation.Thirty cases were selected in each constitution group and during each period.The correlation between qi stagnation constitution and follicle stimulating hormone（FSH）

luteinizing hormone（LH）

estradiol（E2）

prolactin（PRL）

inhibin B（InhB）

anti-Mullerian hormone（AMH） and the maturation index（MI） and maturity value（MV） of tongue off cell were analyzed.Results The differences of FSH

LH

E2 and PRL were statistically significant between two constitution groups during each period（P<0.01）

especially in qi stagnation constitution group.FSH

LH and MV significantly increased with the advance of the perimenopause in both constitution groups（P<0.01）

while E2

PRL

AMH and InhB decreased（P<0.01）.Conclusion The perimenopausal process in qi stagnation women is faster than that in mild women.Qi stagnation constitution is closely related to the change of sex hormones

MI and MV

which could be used as a reference indicator to determine the early perimenopause in qi stagnation women.