Objective To observe the efficacy of Qinghuang Powder

Spleen-Strengthening Kidney-Supplementing Formula（ SKF） and western medicine for myelodysplastic syndrome（ MDS）.Methods Totally 107 cases of outpatient with MDS were included and treated with Qinghuang Powder

SKF and androgens.The treatment lasted for 3 months.The white blood cell（ WBC） count

hemoglobin（ Hb） level and platelet（ PLT） count were detected before and after treatment.The efficacy of blood cells

types

International Prognostic Scoring System（ IPSS） and genetic groups were evaluated.Results There was no significant difference between before and after treatment in WBC and PLT（ P > 0.05）.There was a significant difference between before and after treatment in Hb（ P < 0.05）.There was a significant difference between the efficacy of Hb and WBC（ P < 0.01）.There was a significant difference between the efficacy of Hb and PLT（ P < 0.01）.There was no significant difference between the efficacy of WBC and PLT（ P > 0.05）.There was no significant difference in the efficacy of types

IPSS and genetic groups（ P >0.05）.Conclusion The combo therapy of Qinghuang Powder

SKF and western medicine is effective for MDS and mainly affects erythroid cells.The efficacy is not obviously correlated with types

IPSS and genetic groups.