Discussion on theory that kidney produces marrow in Huangdi Neijing fully illustrates the physiological and pathological relationship among the kidney

marrow and brain

as well as brain related with kidney through quintessential marrow

and traces out the unitive relationship of kidney-marrow-brain. This paper proposes a theory carding to the relationship of kidney-marrow-brain based on the previous studies and makes a preliminary discussion about it combined with the research results of kidney essence. It puts forward kidney-marrow-brain biological axis theory

and thinks that the targets of Chinese medicines which invigorate the kidney should be at the kidney. This paper also confirmes since "kidney produces marrow"

kidney has effects on "brain".