Objective To observe the clinical curative effect of Zhizi（ gardenia） Danqing（ egg white） Formula in treating patients with traumatic swelling pain limbs. Methods Totally 120 cases of traumatic limb swelling pain were randomly divided into a treatment group and a control group

with 60 cases in each. The patients in treatment group were given external application of Zhizi Danqing Formula

and the patients in control group were given external application of Xiaoding Ointment（ 消定膏）. Both groups were dressed one time a day for 12 days

and then followed up for one month. The degree of swelling

pain

and swelling range of the patients in both groups were scored before treatment and 6

12 days after treatment to determine the clinical efficacy. The adverse events were also observed.Results The total effective rate was 83. 33% in the treatment group and 88. 33% in the control group

with no statistically significant difference between the two groups（ P > 0. 05）. After treatment for 6 days and 12 days

the pain

the degree of swelling and swelling range was significantly improved in both groups（ P < 0. 05）. There was no significant difference in pain scores between the two groups after treatment for 6 days and 12 days（ P > 0. 05）. Six days after treatment

the swelling degree and swelling range in the treatment group were significantly lower than those in the control group（ P < 0. 05）

but 12 days after treatment

there was no significant difference in those scores between the two groups（ P > 0. 05）. Conclusion In the treatment of traumatic swelling pain of limbs; Zhizi Danqing Formula has similar curative effect with Xiaoding Ointment; and Zhizi Danqing Formular can relieve limb swelling faster.