基于中医“肾精”学说与间充质干细胞的内在相关性探讨补肾药在哮喘治疗中的作用机理

明溪; 虞坚尔; 李刚; 张新光; 王妍

doi:10.13288/j.11-2166/r.2016.16.003

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基于中医“肾精”学说与间充质干细胞的内在相关性探讨补肾药在哮喘治疗中的作用机理

学术探讨 | 更新时间：2021-11-17

- 基于中医“肾精”学说与间充质干细胞的内在相关性探讨补肾药在哮喘治疗中的作用机理
- Discussion on the Action Mechanism of Tonifying Kidney Medicine in the Treatment of Asthma: Based on the Correlation between the Chinese Medical Theory of “Kidney Essence” and Mesenchymal Stem Cells
- 中医杂志 2016年57卷第16期页码：1358-1362
- 作者机构：
  
  1. 上海中医药大学研究生院
  2. 上海中医药大学附属市中医医院
  3. 云南省中医医院
- 作者简介：
- 基金信息：
  
  国家自然科学基金（81202723）
- DOI：10.13288/j.11-2166/r.2016.16.003
  中图分类号： R259
- 纸质出版：2016
- 稿件说明：
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[1]明溪,虞坚尔,李刚,张新光,王妍.基于中医“肾精”学说与间充质干细胞的内在相关性探讨补肾药在哮喘治疗中的作用机理[J].中医杂志,2016,57(16):1358-1362.

MING Xi, YU Jianer, LI Gang, et al. Discussion on the Action Mechanism of Tonifying Kidney Medicine in the Treatment of Asthma: Based on the Correlation between the Chinese Medical Theory of “Kidney Essence” and Mesenchymal Stem Cells[J]. Journal of Traditional Chinese Medicine2016, 57(16): 1358-1362.
[1]明溪,虞坚尔,李刚,张新光,王妍.基于中医“肾精”学说与间充质干细胞的内在相关性探讨补肾药在哮喘治疗中的作用机理[J].中医杂志,2016,57(16):1358-1362. DOI： 10.13288/j.11-2166/r.2016.16.003.

MING Xi, YU Jianer, LI Gang, et al. Discussion on the Action Mechanism of Tonifying Kidney Medicine in the Treatment of Asthma: Based on the Correlation between the Chinese Medical Theory of “Kidney Essence” and Mesenchymal Stem Cells[J]. Journal of Traditional Chinese Medicine2016, 57(16): 1358-1362. DOI： 10.13288/j.11-2166/r.2016.16.003.

摘要

间充质干细胞（mesenchymal stem cells

MSCs）作为干细胞家族中的重要成员具有多向分化潜能、免疫调节功能及低免疫原性等特点

在哮喘等变态反应性疾病治疗方面有广阔的应用前景。中医"肾精"与MSCs在来源、功能等方面具有诸多相关性

且补肾药对MSCs的增殖分化有明显诱导作用

以此作为切入点

探讨补肾药在哮喘治疗中可能存在的作用机理

为今后开展相关实验研究提供新的思路及理论依据。

Abstract

Mesenchymal stem cells（ MSCs）

as an important member of the family of stem cells

has multidirectional differentiating potential

immunoregulation function and low immunogenicity

thus

they have broad application prospects in the treatment of allergic disease

such as asthma. There is much correlation between Chinese medical theory of "kidney essence "and MSCs in source

function

etc. And the tonifying kidney medicine has obvious induction to proliferation and differentiation of MSCs. As the breakthrough point for above

the authors discuss the possible action mechanism of tonifying kidney medicine in the treatment of asthma to provide new ideas and theory basis for carrying out related experimental study in future.

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