"Heart-kidney interaction" and "water-fire harmonization" as important theories of traditional Chinese medicine have became mature in the Ming and Qing Dynasties. When treating diseases

FU Shan lays emphasis on the relationship between the heart and kidney and puts forward the "mutual promotion within restraint" theory meaning that"there is mutual promotion between heart and kidney though one restricts to the other"; with the idea of "heart-kidney interdependence"

he advocates that the treatment of the heart can help to treat the kidney and vice versa. Based on the "heart-kidney interdependence" theory

he develops many effective formulas in treating menstrual disease

infertility

pregnancy disease and postpartum disease

men′s fatigue and spermatorrhea

vomiting

insomnia and many other diseases.