This paper summarized professor WANG Sumei's experience in syndrome differentiation and treatment of childhood autism. It is believed that

yin

and yang should be initially differentiated， and furthermore the five

zang

-five spirits-five sensory organs is differentiated taking five

zang

（脏） as the core. The location of the disease is at brain orifices， while oppressed vital activity is the key pathogenesis， and phlegm is the main pathological factor. The treatment principle is promoting wisdom， awakening spirit and opening the orifices. To keep

yin

calm，

yang

sound and the five

zang

in harmonization， the methods of enriching and nourishing liver and kidney， supplementing essence and boosting marrow can be used， as well as the methods of fortifying the spleen and nourishing the heart， supplementing

qi

and engendering blood； warming and supplementing the spleen and kidney， and dissolving phlegm to open the orifices； warming and nourishing heart

qi

， and calming the mind； and clearing the heart and calming the liver， dissolving phlegm and calming the mind. It is also suggested to put focus on dissolving phlegm， unblocking the collaterals， promoting wisdom and opening the orifices throughout the treatment. In clinical practice，

Zuogui Beverage

（左归饮），

Dihuang Drink

（地黄饮子），

Guipi Decoction

（归脾汤），

Fugui Yizhi Decoction

（附桂益智汤），

Mengshi Dingzhi Decoction

（礞石定志汤）， and

Kongsheng Zhenzhong Pills

（孔圣枕中丹） can be used.