This paper summarized the clinical experiences of professor ZHAO Jifu in treating tumor diseases with the method of resolving toxins and dissipating masses. Professor ZHAO believes that "binding toxin pathogen" is the fundamental pathogenic mechanisms underlying tumor development. Correspondingly， he developed four methods of resolving toxins and dissipating masses. For tumors with the pathogenic mechanism of excessive heat and internal constraint， the treatment is to clear heat， resolve toxin， and dissipate masses， commonly using

Qingre Sanjie Quyu Decoction

（清热散结祛郁汤）. For tumors with pathogenic mechanism of dampness and toxins accumulating， it is suggested to eliminate dampness， resolve toxin， and dissipate masses， commonly using

Chushi Jiedu Sanjie Formula

（湿解毒散结方）. For tumors with contention and binding between heat and toxins， and vanquished blood and putrid flesh leading to abscess， the method of eliminating abscesses， resolving toxins， and dissipating masses is suggested， and

Neishu Huanglian Decoction

（内疏黄连汤） with modifications is commonly used. For tumors with deficiency in both

qi

and

yin

， the treatment is to nourish

yin

， resolve toxin， and dissipate masses， commonly using postoperative

Qiyin Liangxyu Formula

（气阴两虚方）.